The 10 best startup accelerators in San Francisco

500 Global is a global venture capital firm founded in 2010 that operates a network of startup programs, providing support to founders, mentors, and investors in the early stage and seed stages. Headquartered in San Francisco, California, the accelerator aims to foster the growth and success of startups worldwide.

Alchemist Accelerator is a top venture-backed program focused on nurturing seed-stage ventures monetizing from enterprises. With a strong emphasis on distinctive technical co-founders, it offers structured support, seed investment, and access to a thriving community. Notable alumni include LaunchDarkly, Rigetti Quantum Computing, mPharma, Matternet, and Mightyhive.

IndieBio is a prominent biotech startup accelerator based in San Francisco, California, that was founded in 2014 by Arvind Gupta, Bill Liao, and Sean O'Sullivan. It is recognized as the largest accelerator of its kind and is operated by SOSV, providing seed funding and comprehensive support to promising biotech startups.

HAX is a startup accelerator located in San Francisco, California, that focuses on supporting and investing in early-stage ventures in the hard tech industry. Founded in 2011 by a team of experienced entrepreneurs and venture capitalists, HAX is part of SOSV's venture program and offers seed funding and mentorship to help startups bring their innovative hardware technologies to market.

AngelPad is a renowned seed-stage accelerator program and MicroVC Fund founded in 2010 by Thomas Korte and Carine Magescas. The program focuses on finding product-market fit and validating target markets for startups. With consistent top rankings, including being ranked #1 U.S. Accelerator by MIT/Rice University's Accelerator Rankings Project, AngelPad has established itself as a leading force in the startup ecosystem.

SAP.iO is a startup accelerator based in San Francisco that provides support to early-stage ventures, seed-stage companies, and established ventures looking to scale their businesses with the help of SAP's expertise and resources. Led by Ram Jambunathan, SAP.iO aims to empower innovators and facilitate their growth within the SAP ecosystem.

Expa is a startup accelerator based in San Francisco, California, that provides expertise, access to resources, and funding to early-stage startups in order to help them thrive. Founded in 2013 by Garrett Camp and Kristin Stannard, Expa focuses on supporting and nurturing promising ventures in their early stages of development, acting as both a venture studio and a venture capital fund.

Launch Academy is a Vancouver-based non-equity startup accelerator providing a supportive environment, mentorship, and resources for entrepreneurs to accelerate the growth of their startups. Founded in 2012 by Alex Chuang, Mike Edwards, Ray Walia, and Roger Patterson, the accelerator offers networking opportunities and assistance in securing funding to help entrepreneurs succeed.

Nex Cubed is an early-stage venture and seed accelerator based in San Francisco, California that provides investment and partnership opportunities to digitally-enabled startups, helping them accelerate their growth and scale their businesses. Founded in 2016 by Bill Malloy, Kelsey Morgan, and Kip Quackenbush, Nex Cubed serves as an innovation partner, offering extensive support and mentorship to its portfolio companies.

Desafia is a startup accelerator that originally started in Spain but has now expanded its operations to San Francisco, California. Since its establishment in 2011, it has been focused on supporting early-stage ventures and providing seed funding to promising startups.